Although the analysts have now acquired high level of expertise in routine application of this technique, however, developing a validated stability-indicating assay method as well as impurity profiling still remains a challenge. Since every analyst does not have access to latest publications on application of HPLC in Pharmaceutical Analysis and mentors being rare commodity, detailed analytical procedures for 452 formulations have been described in Volumes 3 and 4 in sequel to Volumes 1 and 2. Majority of the methods are reported to have been validated, still the analysts are advised to optimize the method under available laboratory facilities before adopting for regular use. All the four volumes in series on HPLC Quantitative Analysis of Pharmaceutical Formulations contain detailed analytical procedures for 1082 multi-component formulations primarily oriented to problem-solving and should help the analyst in develop in methods for newer formulations.
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