Synopsis
Bringing a compound to market quickly and profitably requires efficient and cost-effective processes for preparing large amounts of the target compound and intermediates. The key to rapid and successful process development is avoiding scale-up problems. However, an understanding of scale-up issues is rarely taught in academia and may take years of industrial experience to acquire. Practical Process Research & Development teaches how to anticipate and avoid these problems when processes are being scaled up from the research lab or pilot plant. The approach is pragmatic, with a minimum of theory and over 100 practical scale-up tips. Many tables and detailed reaction schemes allow the reader to identify critical processing steps quickly. This practical guide is essential reading for chemists and chemical engineers involved in industrial process research and/or process development and for anyone seeking a clearer understanding of how and why process R&D is conducted in the pharmaceutical and fine chemicals industries.
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