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Algorithms for Sample Preparation with Microfluidic Lab-on-Chip (River Publishers Series in Biomedical Engineering) - Hardcover

Bhattacharjee, Sukanta; Bhattacharya, Bhargab B.; Chakrabarty, Krishnendu

 
9788770220552: Algorithms for Sample Preparation with Microfluidic Lab-on-Chip (River Publishers Series in Biomedical Engineering)
Hardcover
ISBN 10: 8770220557 ISBN 13: 9788770220552
Publisher: River Publishers, 2019

Synopsis

Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design.

Algorithms for Sample Preparation with Microfluidic Lab-on-Chip bridges the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips.

Technical topics discussed in the book include:

- Basics of digital and flow-based microfluidic lab-on-chip
- Comprehensive review of state-of-the-art sample preparation algorithms
- Sample-preparation algorithms for digital microfluidic lab-on-chip
- Sample-preparation algorithms for flow-based microfluidic lab-on-chip

"synopsis" may belong to another edition of this title.

About the Authors

Sukanta Bhattacharjee is with Indian Statistical Institute, India.

Bhargab B. Bhattacharya is with Indian Statistical Institute, India.

Krishnendu Chakrabarty teaches Computer Science at Duke University.

"About this title" may belong to another edition of this title.

Publisher
River Publishers
Publication date
2019
Language
English
ISBN 10 
8770220557
ISBN 13 
9788770220552
Binding
Hardcover
Edition number
1
Number of pages
250