Algorithms for Sample Preparation with Microfluidic Lab-on-Chip (River Publishers Series in Biomedical Engineering) - Hardcover

Bhattacharjee, Sukanta; Bhattacharya, Bhargab B.; Chakrabarty, Krishnendu

Hardcover

ISBN 10: 8770220557 ISBN 13: 9788770220552

Publisher: River Publishers, 2019

Synopsis

Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip

About this title

About the Author

Sukanta Bhattacharjee, Bhargab B. Bhattacharya, Krishnendu Chakrabarty

Edition details

• Publisher: River Publishers
• Publication date: 2019
• Language: English
• ISBN 10: 8770220557
• ISBN 13: 9788770220552
• Binding: Hardcover
• Edition number: 1
• Number of pages: 178