Bursting: The Genesis of Rhythm in the Nervous System - Hardcover

Hardcover

ISBN 10: 981256506X ISBN 13: 9789812565068

Publisher: World Scientific Publishing Company, 2005

Synopsis

Neurons in the brain communicate with each other by transmitting sequences of electrical spikes or action potentials. One of the major challenges in neuroscience is to understand the basic physiological mechanisms underlying the complex spatiotemporal patterns of spiking activity observed during normal brain functioning, and to determine the origins of pathological dynamical states such as epileptic seizures and Parkinsonian tremors. A second major challenge is to understand how the patterns of spiking activity provide a substrate for the encoding and transmission of information, that is, how do neurons compute with spikes? It is likely that an important element of both the dynamical and computational properties of neurons is that they can exhibit bursting, which is a relatively slow rhythmic alternation between an active phase of rapid spiking and a quiescent phase without spiking. This book provides a detailed overview of the current state-of-the-art in the mathematical and computational modeling of bursting, with contributions from many of the leading researchers in the field.

About this title

Review:

The excitement generated by this collection stems from the demonstration that interdisciplinary teams are forming to tackle the outstanding issues.?

About this edition

• Publisher: World Scientific Publishing Company
• Publication date: 2005
• ISBN 10: 981256506X
• ISBN 13: 9789812565068
• Binding: Hardcover
• Number of pages: 420
• Editor: Coombes Steve, Bressloff Paul