Title: Activity-Based Protein Profiling (Current Topics in Microbiology and Immunology, 420) [Hardcover] Cravatt, Benjamin F.; Hsu, Ku-Lung and Weerapana, Eranthie (eng)
Publisher: Springer
Publication Date: 2019
Language: English
ISBN 10: 3030111423
ISBN 13: 9783030111427
Binding: Hardcover
Condition: new
Weight: 0.81 kilograms

About this title

Synopsis

This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions.

About the Author

Benjamin F. Cravatt, Ph.D.

Department of Chemistry

The Scripps Research Institute

La Jolla, CA, USA

cravatt@scripps.edu

Ku-Lung Hsu Ph.D.

University of Virginia School of Medicine

Department of Chemistry

Charlottesville, VA, USA

kh4ch@virginia.edu

Eranthie Weerapana Ph.D.

Boston College

Merkert Chemistry

Chestnut Hill, MA, USA

eranthie@bc.edu

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