2nd edition. Text unmarked and clean, pages bright. Binding is tight, sturdy, and square. Bumping to head of spine, light bumping to bottom outer corner, otherwise shelfwear is very minor. Ships same or next business day from Dinkytown in Minneapolis, Minnesota. Due to the size/weight of this book extra charges may apply for international shipping.

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Bibliographic Details

Title

Adaptive Design Theory and Implementation Using SAS and R (Chapman & Hall/CRC Biostatistics Series)

Publisher

Chapman and Hall/CRC

Publication Date

2014

Language

English

ISBN 10

1482256592

ISBN 13

9781482256598

Binding

Hardcover

Edition

Second.

Condition

Very Good

Dust Jacket Condition

No Dust Jacket Issued

Seller catalogs

Mathematics

About this title

Synopsis

Get Up to Speed on Many Types of Adaptive Designs

Since the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new developments, Adaptive Design Theory and Implementation Using SAS and R, Second Edition offers a detailed framework to understand the use of various adaptive design methods in clinical trials.

New to the Second Edition

Twelve new chapters covering blinded and semi-blinded sample size reestimation design, pick-the-winners design, biomarker-informed adaptive design, Bayesian designs, adaptive multiregional trial design, SAS and R for group sequential design, and much more
More analytical methods for K-stage adaptive designs, multiple-endpoint adaptive design, survival modeling, and adaptive treatment switching
New material on sequential parallel designs with rerandomization and the skeleton approach in adaptive dose-escalation trials
Twenty new SAS macros and R functions
Enhanced end-of-chapter problems that give readers hands-on practice addressing issues encountered in designing real-life adaptive trials

Covering even more adaptive designs, this book provides biostatisticians, clinical scientists, and regulatory reviewers with up-to-date details on this innovative area in pharmaceutical research and development. Practitioners will be able to improve the efficiency of their trial design, thereby reducing the time and cost of drug development.

About the Author

Chang, Mark

"About this title" may belong to another edition of this title.

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