A brief history of drug design presented to make clear that there are fashions in this important field and that they change rather rapidly. This is due in part to the fact that the way that a new paradigm is accepted in a drug company often does not depend on its scientific merit alone.

About the Author

Gisbert Schneider, Ph.D., Beilstein Professor of Cheminformatics, Institute of Organic Chemistry, Johann Wolfgang Goethe-University, Frankfurt, Germany. Sung-Sau So, Ph.D., F. Hoffmann-La Roche, Inc. Discovery Chemistry, Nutley, New Jersey, U.S.A.

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