Title: Addiction (Cold Spring Harbor Perspectives in Medicine)
Publisher: Cold Spring Harbor Perspective
Publication Date: 2012
Language: English
ISBN 10: 1936113473
ISBN 13: 9781936113477
Binding: Gebundene Ausgabe
Condition: Wie neu
Dimensions: 25.6 centimeters width by 18.4 centimeters height by 2.4 centimeters depth
Weight: 815 grams

About this title

Synopsis

Drug and alcohol abuse elicits significant biological changes in the brain that drive compulsive behavior and lead to addiction. Abrupt cessation leads to withdrawal, craving, and relapse. A complete understanding of the brain changes produced by abused substances is therefore necessary if we are to develop treatments for drug dependence.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine explores the biological basis of addiction to alcohol, nicotine, and other psychoactive drugs. Contributors describe the molecular targets of these drugs, the resulting changes to neural networks, and the various genetic, developmental, and behavioral factors that influence the progression from abuse to addiction. Animal models of addictive behavior and techniques to dissect neural circuits are also described.

This volume includes discussion of compounds currently used or under development to treat drug dependence. Thus, it is an indispensable reference for neuroscientists and all who are interested in reducing the public health burden of substance abuse.

About the Author

R. Christopher Pierce is Professor of Neuroscience in Psychiatry Department of Psychiatry at the University of Pennsylvania.

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