Advanced Drug Delivery Systems in Management of Chronic Obstructive Pulmonary Disease
Language: English
Published by CRC Press, 2025
- Hardcover
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- Title
- Advanced Drug Delivery Systems in Management of Chronic Obstructive Pulmonary Disease
- Publisher
- CRC Press
- Publication year
- 2025
- Condition
- New
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 1032812591
- ISBN 13
- 9781032812595
This book offers a comprehensive overview of the epidemiology, etiology, and pathophysiology of chronic obstructive pulmonary disease (COPD). It addresses the limitations of existing drug delivery methods and explores advanced delivery systems to overcome these challenges, providing an exhaustive account of their intricate mechanisms. The introductory chapters elucidate pathways responsible for COPD progression, followed by a detailed analysis of established biomarkers and potential targets in contemporary COPD therapy. Subsequent chapters provide insights into ongoing treatment modalities, their efficacy, drawbacks, and prospective solutions to counter the setbacks of COPD therapy. The subsequent section covers state-of-the-art drug delivery technologies and novel drug formulations designed to enhance drug deposition and absorption in COPD lungs. It further explores a methodical yet coordinated explanation of targeted personalized therapies and emerging approaches, including nanoparticles, polymeric carriers, and vesicular delivery systems. Toward the end, the book discusses ongoing and completed clinical trials encompassing the management of COPD through advanced drug delivery approaches. It serves as a valuable resource for professionals, scientists, academicians, and clinicians specializing in respiratory health.
- Provides an in-depth understanding of the epidemiology, etiology, and pathophysiology of Chronic Obstructive Pulmonary Disease (COPD)
- Delve into pathways responsible for COPD progression, conducting a detailed analysis of established biomarkers and potential targets in contemporary COPD therapy
- Offer insights into ongoing treatment modalities, evaluating their efficacy, drawbacks, and proposing prospective solutions to counter the setbacks of COPD therapy
- Systematically organizes information on state-of-the-art drug delivery technologies and novel formulations designed to enhance drug deposition and absorption in COPD lungs
- Presents a methodical explanation of targeted personalized therapies and emerging approaches, including nanoparticles, polymeric carriers, and vesicular delivery systems
"Synopsis" may belong to another edition of this title.
About the Author
Dr. Parteek Prasher, an Associate Professor in the Department of Chemistry at the University of Petroleum & Energy Studies, possesses 8 years of research experience in medicinal chemistry and biomaterials. Leading a research team, he focuses on developing rationally designed molecules to target various disorders, including inflammation, cancer, and antimicrobial multidrug resistance. Dr. Prasher has received prestigious fellowships and awards, including the Junior/Senior Research Fellowship by the Council of Scientific and Industrial Research (2012–2015) and the TARE Fellowship by the Department of Science and Technology-Science and Engineering Research Board (DST-SERB) for three years.
Dr. Mousmee Sharma, an Assistant professor in the Department of Chemistry at Uttaranchal University, possesses over 5 years of research experience in physical chemistry and biomaterials, with a focus on bio membranes. Her recent research centres on developing mucoadhesive materials for drug delivery across physiological mucus barriers. Dr. Mousmee, a 'Gold Medallist' in post-graduation, has authored 80 research and review articles and 20 book chapters in reputable journals
Dr. Gang Liu completed his Bachelor of Science in Biotechnology at Tianjin University of Commerce in 2008, followed by a Master of Science in Biotechnology at the University of Wollongong in 2011. He earned his PhD in Immunology and Microbiology at the University of Newcastle (Australia) in 2016, focusing on airway remodeling in respiratory diseases such as chronic obstructive pulmonary disease (COPD), severe asthma, and idiopathic pulmonary fibrosis (IPF). Dr. Liu conducted postdoctoral research from 2016–2017, investigating inflammation's role in respiratory diseases, and later studied tissue structure changes and remodeling in the gut-lung crosstalk at Hunter Medical Research Institute (HMRI) from 2017–2019. Since 2019, he has held a tenure position as a lecturer at the University of Technology (UTS), leading the fibrosis program at the Center for Inflammation in the UTS/Centenary Institute. Dr. Liu was awarded a CREATE Hope Fellowship from Lung Foundation Australia (2022-2023) and was promoted to senior lecturer at UTS in early 2023. Currently, he teaches and coordinates immunology and pathology subjects at UTS while supervising three PhD students. His ongoing research focuses on understanding the mechanisms of lung fibrosis in various lung diseases and identifying new therapeutic options.
Dr. Amlan Chakraborty specializes in unraveling the mechanisms of innate immune cells in airway inflammation and remodeling linked to chronic allergic airway diseases, particularly asthma. He holds a research master's degree and a PhD, focusing on developing immunomodulators to target airway inflammation in acute lung injury and asthma. As a postdoctoral research associate, he investigated peptide-conjugated nanoparticles in asthma-related inflammation. Joining the Fibrosis Group at Monash Biomedicine Discovery Institute in 2020, he secured two industry-funded fellowships to explore induced pluripotent stem cells' role in pulmonary fibrosis and understand epithelial cell repair in chronic allergic airway disease. Dr. Chakraborty has over 20 publications, 7 pending patents, and has attracted $200K in commercial funding. His post-PhD research concentrates on using nanoparticles, including serelaxin-conjugated ones, to attenuate airway inflammation and target airway remodelling in pulmonary fibrosis and asthma. He also investigates the role of pulmonary myeloid cells in asthma-associated airway remodeling using functionalized nanoparticles, traceable through innovative imaging techniques. Recently, he has expanded his research interest to explore circadian mechanisms in asthma.
Dr. Kamal Dua is an Associate Professor in the Discipline of Pharmacy at UTS. Dr Dua has been recognised and named as one of Australia’s Top 250 researchers in 2025 and 2024 in Research Magazine by the Australian in the research discipline of Health and Medical sciences, and #1/research leader in the area of Pharmacology and Pharmacy (2025) and Toxicology (2024) respectively. With over 17 years of research experience, he has specialised in drug delivery targeting inflammatory diseases. Additionally, Dr Dua also leads drug delivery research at the Woolcock Institute of Medical Research. In this role, he focuses on advancing targets identified in research projects to develop innovative formulations, taking the first steps toward clinical translation. Dr. Dua’s research encompasses two complementary areas: drug delivery and immunology. His work explores how these disciplines can mutually benefit, contributing to the goal of promoting longer and healthier lives for the community. His commitment to synergy is reflected in his extensive publication record in reputable journals. Dr Dua’s research interests are centered on harnessing the pharmaceutical potential of modulating critical regulators, such as interleukins and microRNAs. He also specialises in developing new and effective drug delivery formulations for managing inflammation in chronic airway diseases and cancer.
"About the title" may belong to another edition of this title.
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Moluna GmbH
Engberdingdamm 27
Greven, Germany 48268
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Standard Business Terms and customer information/ data protection declaration
Revocation right for consumers
(A ‘consumer’ is any natural person who concludes a legal transaction which, to an overwhelming extent, cannot be attributed to either his commercial or independent professional activities.)
Instructions for revocation
Revocation right
You have the right to revoke this contract within one month without specifying any reasons.
The revocation period is one month with effect from the day,
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on which you or a third party nominated by you, which is not the carrier, had taken possession of the products, provided you had ordered one or more products within the scope of a standard order and this/these product/products is/are delivered uniformly;
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In order to exercise your revocation right, you must inform us (Moluna GmbH, Engberdingdamm 27, 48268 Greven, Telephone number: 02571/5 69 89 33, Fax number: 02571/5 69 89 30, E-Mail address: abe@moluna.de) of your decision to revoke this contract by means of a clear declaration (e.g. a letter sent via post, fax or email). You can use the enclosed specimen revocation form for this, which however is not mandatory.
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The revocation right is not available for contracts
for delivery of products, which are not prefabricated and for whose manufacturing an individual selection or stipulation by the consumer is important or which are clearly tailored to the personal requirements of the consumer;
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Specimen - revocation form
(If you wish to revoke the contract, please fill up this form and send it back to us.)
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To Moluna GmbH, Münsterstr. 105, 48268 Greven, Fax number: 02571/5 69 89 30, Email address: abe@moluna.de :
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I/we () herewith revoke the contract concluded by me/ us () regarding the purchase of the following products ()/
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Ordered on ()/ received on ()
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Insofar as you are an entrepreneur, the following shall apply in deviation from the above warranty provisions:
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b) In the event of defects, we shall, at our discretion, provide warranty by rectification of the defect or subsequent delivery. If the rectification of defects fails, you may, at your option, demand a reduction in price or withdraw from the contract. The rectification of defects shall be deemed to have failed after a second unsuccessful attempt, unless the nature of the goods or the defect or other circumstances indicate otherwise. In the event of rectification of defects, we shall not be obliged to bear the increased costs arising from the transport of the goods to a place other than the place of performance, unless such transport is in accordance with the intended use of the goods.
c) The warranty period shall be one year from delivery of the goods. The shortening of the period shall not apply
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(3) The provisions of the UN Convention on Contracts for the International Sale of Goods are explicitly inapplicable.
II. Customer information
- Identity of the seller
Moluna GmbH
Engberdingdamm 27
48268 Greven
Germany
Telephone: 02571/5698933
E-Mail: abe@moluna.de
- Information regarding the conclusion of the contract
The technical steps associated with the conclusion of the contract, the contract conclusion itself and the correction options are executed in accordance to the regulations "conclusion of the contract" in our standard business terms (part I.).
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6.2 If you are a consumer, the following is statutorily regulated: The risk of the sold item accidentally being destroyed or degraded during shipping only passes over to you when the item in question is delivered, regardless of whether or not the shipping operation is insured. This condition does not apply if you have independently commissioned a transport company that has not been specified by us or a person who has otherwise been appointed to execute the shipping operation.
If you are a businessman, the delivery and shipping operations take place at your own risk.
- Statutory warranty right
Liability for defects is governed by the “Warranty” provisions in our General Terms and Conditions of Business (Part I).
last update: 01.01.2022
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last update: 10.01.2022