Advanced oxidation processes are entering a new phase in which classical oxidation chemistry is being integrated with process optimization, hybrid treatment trains, and digital decision-support tools. This Topic focuses on how oxidation-based technologies are evolving from laboratory-scale pollutant removal methods into broader environmental engineering solutions for water, wastewater, and related industrial applications. The contributions highlight both established systems, such as ozonation, UV-based oxidation, and electrochemical treatment. A central message is that future progress will depend not only on removal efficiency, but also on energy demand, catalyst durability, cost, operational resilience, and applicability to real matrices. The Topic also reflects a wider shift toward intelligent water systems, where treatment is increasingly coupled with monitoring, forecasting, and optimization. In this context, advanced oxidation is no longer viewed as an isolated technology, but as part of integrated strategies for water reuse, environmental protection, and sustainable process engineering. Overall, the Topic captures a field moving toward more selective, practical, and scalable solutions for complex contamination challenges.

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