Advanced Vaccine Research: Methods for the Decade of Vaccines

Since the publication of Fabio Bagnoli's and Rino Rappuoli's first book in 2011 (Vaccine Design: Innovative Approaches and Novel Strategies; ISBN 978 1 904455 74 5), the field of vaccinology has advanced significantly. The application of new sophisticated 'omics' technologies and the use of pioneering approaches have yielded a wealth of new data. This new book distills the most important new findings to provide a timely overview of the field. Written by leading experts in the field, each chapter affords a critical insight to a particular topic, reviews current research, discusses future direction, and aims to stimulate discussion. The provision of extensive reference sections in the book's chapters positively encourages readers to pursue the subject in greater detail. The book has retained the format of the 2011 book and is divided into two main parts. The first section explores in considerable depth the key innovations that are dramatically changing the field, both for preclinical as well as clinical vaccine research fields. Some of the topics covered include: the use of deep sequencing * cellular screens to interrogate the human T and B cell repertoires * comparative genomics to track bacterial pathogens * quantitative proteomics * structural biology * novel strategies for vaccine administration * T-cell inducing vaccines * etc. The second section focuses on diseases for which current medical treatment is not very effective, as well as diseases that could be either prevented or treated by vaccination. The book's contributors believe that these will be the vaccines of the future, the 'vaccines for 2020.' This book is essential reading for everyone working in vaccine R and D in academia, biotechnology companies, and the pharmaceutical industry, and it is a recommended volume for all microbiology libraries. *** Librarians: ebook available on ProQuest and EBSCO [Subject: Microbiology, Vaccinology, Life Science