Advances in Glycobiotechnology

This book reviews the latest trends in glycobiotechnology, it offers an authoritative discussion about future directions of glycoengineering, and it provides a comprehensive overview about the current and emerging approaches to identify, quantify and characterize glycosylated proteins.

Divided into 14 chapters, the book outlines recombinant glycoprotein expression in mammalian cells, insect cells, yeast, and bacterial systems. It covers the chemical and enzymatic syntheses of glycans and glyconjugates, and addresses the impact of glycosylation on protein function for the development of biologicals including vaccines. In the final chapters of the book, readers will discover more about the state-of-the-art in glycomics, glycoproteomics and glycan array technologies.

Dr. Erdmann Rapp is heading the Bio/Process Analytics team of the Bioprocess Engineering Department at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg and founder, CEO & CSO of glyXera, providing tailored cutting-edge glycoanalytical products and services. He is an experienced researcher, inventor, mentor and university lecturer. He and his team are working on the development and implementation of innovative bio/process analytics - in particular, on sophisticated tools for proteomics, glycoproteomics and glycomics - for a deeper understanding of biological and biotechnological processes. Dr. Rapp’s successful research is documented by more than 120 peer-reviewed papers and book chapters, and 8 patents.