Advancing Methods for Biomolecular Crystallography

Randy Read

ISBN 10: 9400762313 / ISBN 13: 9789400762312

Published by Springer Netherlands, Springer Netherlands, 2013

About this Item

Druck auf Anfrage Neuware - Printed after ordering - This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web. Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis. These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome. Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.

Seller Inventory # 9789400762312

Bibliographic Details

• Title: Advancing Methods for Biomolecular Crystallography
• Publisher: Springer Netherlands, Springer Netherlands
• Publication Date: 2013
• Language: English
• ISBN 10: 9400762313
• ISBN 13: 9789400762312
• Binding: Buch
• Condition: Neu
• Dimensions: 241W x 160H x 25D millimeters 241 millimeters width by 160 millimeters height by 25 millimeters depth
• Weight: 729 grams

About this title

Synopsis

This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web.  Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis.  These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome.  Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.