Alcohol, Cell Membranes, and Signal Transduction in Brain

Language: English

Published by Springer, Springer Okt 2012, 2012

1461360528 / 9781461360520

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This item is printed on demand - Print on Demand Titel. Neuware -Alcohol abuse and alcoholism are international problems whose costs economical ly, psychologically and medically have been well documented. Alcohol is a unique drug in that the effects of excessive use can have a deleterious effect on most if not all organs of the body. The brain is one of the organs most affected by excessive alcohol consumption. Effects on the brain can be seen in cognitive function, brain structure and neurochemistry. Over the past few years, there have been significant advances made in understanding how alcohol affects brain neurochemistry. This book examines four major areas, i. e. , membrane lipids, receptors and ion channels, second messengers, and gene expression, where significant advancements have been made. The book is divided into four sections based on the four major areas. In each section, data are examined that cover a range of approaches from in vitro to in vivo studies. The section on membrane lipids includes recent developments in how ethanol affects membrane cholesterol domains, polyunsaturated fatty acids, the cause and consequences of phosphatidylethanol formation, and the modulation of membrane protein function by lipid-protein interaction. The second section comprises chapters on NMDA and 5-HT3 receptors, including new aspects on alcohol neurotoxicity and the molecular heterogeneity that may underlie differences in alcohol sensitivity as well as chapters on GABA-gated chloride flux, and calcium channels.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 340 pp. Englisch.

Seller Inventory # 9781461360520

Title
Alcohol, Cell Membranes, and Signal Transduction in Brain
Author
Christer Alling
Publisher
Springer, Springer Okt 2012
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1461360528
ISBN 13
9781461360520
Item weight
641 grams
Dimensions
254x178x19 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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