The novel coronavirus named the SARS-CoV-2 or COVID-19, the coronavirus is a cluster of viruses, and it consists of various proteins, and the spike protein is identified as the leading protein and mediates as the entry inside the host body and causes SARS-CoV-2 syndrome. The spike protein consists of two domains, named S1 and S2. The receptor binding takes place at the S1 area and is liable for acknowledgment and binds to the host cell receptor and the S2 domain responsible for fusion. The coronavirus is recognized as a cluster of enveloped viruses consisting of nonsegmented, single-stranded, and positive-sense RNA genomes that replicate in the cytoplasm, the SARS-CoV-2 appeared in 2019 Wuhan, China in the completion of December month and named it as a 2019nCoV or COVID-19. In this book, we have mentioned various essential aspects of SARS-CoV-2. Also, the recent testing devices such as the Feluda test, molecular test, serology test, and rt-PCR and also describe the case study of different countries and the symptoms, causes of the novel coronavirus. This book contains a brief discussion of various drugs.

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