Synopsis
Biological Applications of Raman Spectroscopy Volume 1: Raman Spectra and the Conformations of Biological Macromolecules Edited by Thomas G. Spiro The first of the landmark volumes focusing on biological Raman applications, Volume 1 provides an incisive look at the current research surrounding the conformations of biological macromolecules. Volume 1 considers the varieties of macromolecules—proteins, nucleic acids, and lipids—in isolation and in the organized biological assemblies of ocular lenses, viruses, and membranes. The collective vibrational modes of macromolecules are considered theoretically, and there is a review of the promising area of vibrational optical activity. 1987 (0 471-81573-X) 352 pp. Volume 2: Resonance Raman Spectra of Polyenes and Aromatics The importance of the resonance Raman effect for biological applications is that it can provide dramatically increased sensitivity and selectivity The theory of the effect is presented in Volume 2, which also explores applications to rhodopsin, to the purine and pyrimidine bases of nucleic acids, to the peptide backbone and chromophoric side chains of proteins, to flavins, and, finally, to the introduction of resonance Raman labels into biological systems. 1987 (0 471-81574-8) 367 pp. Volume 3: Resonance Raman Spectra of Heme and Metalloproteins Heme proteins have provided an especially rich opportunity for Raman studies. Volume 3 describes in detail various aspects of work in this area, including applications to chlorophylls and nonheme metalloproteins. Coverage includes heme protein structure and the iron-histidine stretching mode; Raman scattering by cytochrome oxidase and by heme a model compounds; chlorophylls and the photosynthetic membrane; resonance Raman spectroscopy of blue copper proteins; and nonheme respiratory proteins. 1988 (0 471-81575-6) 565 pp.
About the Author
About the editors JEANETTE G. GRASSELLI is a Distinguished Visiting Professor and Director of Research Enhancement at Ohio University, Athens, Ohio. Until recently, she served as research director of the Research and Development Department of BP America (formerly Standard Oil). She has lectured extensively at universities in the U.S. and abroad on the subject or molecular spectroscopy and problem solving and published seventy articles and six books in the field of molecular spectroscopy. Dr. Grasselli is currently chair of the Analytical Division and a Fellow of the American Association for the Advancement of Sciences. The recipient of numerous distinctions and awards, she has been honored with the Garvan Medal of the American Chemical Society (1986), an award given annually to the U.S.’s outstanding woman chemist. Dr. Grasselli received a BS in chemistry from Ohio University, an MS from Case Western Reserve University, a DSc (Hon.) from Ohio University and Clarkson University, and a DEngr (Hon.) from Michigan Technological University BERNARD J. BULKIN is currently Head of Oil Research at The British Petroleum Research Centre, Sun-bury, UK, a division of British Petroleum Company responsible for fuels, lubricants, and processing research and development. Dr. Bulkin also served for several years on the faculty of the City University of New York and as Dean of Arts and Sciences at the Polytechnic Institute of New York. The author of more than 80 publications, Dr. Bulkin’s research has included work in vibrational spectroscopy, imaging technology, polymers, and liquid crystals. He is a member of the ACS Analytical Chemistry Editorial Advisory Board. In 1989, Dr. Bulkin was elected a Fellow of the Royal Society of Chemistry. Dr. Bulkin received a BS from the Polytechnic Institute and a PhD from Purdue University.
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