Angiogenesis: Mechanisms and Clinical Implications: A Comprehensive Analysis with Focus on Wound Healing, Cancer, and Oral Pathologies

This book provides a comprehensive overview of angiogenesis, the process of new blood vessel formation from pre-existing vessels. It explains the molecular and cellular mechanisms underlying angiogenesis and the key regulatory factors involved, such as VEGF and angiopoietins. The physiological role of angiogenesis in wound healing is discussed, alongside its pathological role in cancer, where it facilitates tumor growth and metastasis. A dedicated section highlights the role of angiogenesis in oral cavity diseases, including periodontitis, oral cancer, and chronic inflammation. The book also explores methods for validating angiogenesis, including histological and molecular techniques, and examines the principles of anti-angiogenic therapy. Bridging basic science and clinical applications, this book serves as a valuable resource for medical, dental, and life science students, researchers, and clinicians. It emphasizes the dual role of angiogenesis in health and disease, and its relevance in future diagnostic and therapeutic developments.