The study of animal virus pathogenesis is an important and rapidly developing area, especially since the emergence of AIDS and the consequent increase in research activity. Because this work takes place at the interface between virology and immunology, understanding viral pathogenesis requires knowledge and use of techniques drawn from several disciplines. This book provides up-to-date coverage of the way that viral tropism, viral expression, and viral infectivity are assayed. It describes the identification of antiviral cytotoxic T cells, natural killer and free antibody responses. It also covers making vaccinia/viral cDNA for immunologic target recognition, and tissue and whole animal in situ hybridization.

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'a very useful methods book, with each chapter containing a clear and concise description of the various protocols' Anthony Nash, University of Cambridge, Tibtech, December 1991 (vol.9)

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