This Reprint brings together cutting-edge contributions that address the acute and evolving challenge of antimicrobial resistance in the intensive care setting. Critically ill patients in Intensive Care Units (ICUs) face a disproportionate burden of infections caused by multidrug-resistant organisms, demanding a rigorous appraisal of both epidemiological trends and therapeutic strategies. In this collection we highlight three interconnected domains: (1) the dynamic epidemiology of key pathogens in ICUs, including Gram-negative bacilli, non-fermenters, and other high-risk bacteria; (2) advances in microbiological diagnostics-encompassing rapid molecular methods, phenotypic detection, and real-time therapeutic guidance techniques; and (3) optimization of antimicrobial therapy grounded in pharmacokinetics/pharmacodynamics, novel agents, and stewardship frameworks tailored to the critical-care environment. The aim is to offer clinicians, microbiologists, and researchers a coherent resource that merges mechanistic insights with practical treatment algorithms for complex resistance mechanisms. By integrating surveillance data, therapeutic case series, and reviews of emerging antimicrobials, this Reprint supports evidence-based decision-making and fosters interdisciplinary collaboration in the fight against antimicrobial resistance in intensive care.

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We first started out as ?The Paperback Exchange,? a chain of physical bookstores where we would part exchange your beloved books for new stories to transport you to faraway places. However, as shopping started to evolve to online shops and marketplaces, we bid our stores goodbye to become ?PBShop.? This transition has only allowed us to blossom as we now ship thousands of titles to book lovers across the globe. We pride ourselves in being a community of local book lovers which allows our passion and devotion to shine in everything we do. In 2020 we not only celebrated our 20th birthday but our 1st birthday as being completely employee owned after becoming an E.O.T in September 2019. We are proud to be different and embrace standing apart on a book mountain by working from a virtual inventory which allows us to provide thousands of books that may be difficult to get for your bookshelf or your studies. Working with a number of different suppliers allows us to explore other avenues such as puzzles, sheet music and even stationery so we really do have something for everyone. Life is about being versatile in all realms of existence. If this is your first visit or you are a returning customer, we would like to welcome you to the PBShop family, for there is no friend as loyal as a book. We are a company who put our customers at the centre of everything we do as we understand the importance of reading because once you learn to read, you will forever be free. There are a whole lot of things in this world of ours that we are yet to explore, which is why we will forever inspire curious minds.

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