Antisense Technology, Part B: Applications (Volume 314) (Methods in Enzymology, Volume 314)

Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods which inhibit gene expression permit studies probing the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedically-oriented research.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences.

Praise for the Series "The Methods in Enzymology series represents the gold-standard." (Neuroscience)

"Incomparably useful." (Analytical Biochemistry)

"...including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page." (Bio/Technology)

"...It should be on the shelves of all libraries in the world as a whole collection." (Chemistry in Industry)

"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation..." (American Society of Microbiology News)

"If we had some way to find the work most often consulted in the laboratory, it could well be...Methods in Enzymology." (Enzymologia)

"A series that has established itself as a definitive reference for biochemists." (Journal of Chromatography)