Application of Biological Markers to Carcinogen Testing

Harry A. Milman

ISBN 10: 1461337925 / ISBN 13: 9781461337928

Published by Springer US, 2011

About this Item

Druck auf Anfrage Neuware - Printed after ordering - InhaltsangabeWelcoming Remarks.- An Overview of Current Research Efforts on the Application of Biological Markers to Carcinogen Testing.- In Vivo Tests.- Chairman's Overview on In Vivo Tests.- The Occurrence of Neoplasms in Long-Term In Vivo Studies.- Markers of Liver Neoplasia - Real or Fictional .- Early Morphologic Markers of Carcinogenicity in Rat Pancreas.- Rodent and Human Models for the Analysis of Intestinal Tumor Development.- Effect of Diet on Intestinal Tumor Production.- Tumor Antigens as Markers for Carcinogens.- In Vitro Tests.- Chairmen's Overview on In Vitro Tests.- Biochemistry and Biology of 2-Acetyl-Aminofluorene in Primary Cultures of Adult Rat Hepatocytes.- Relating In Vitro Assays of Carcinogen-Induced Genotoxicity to Transformation of Diploid Human Fibroblasts.- Evaluation of Chronic Rodent Bioassays and Ames Assay Tests as Accurate Models for Predicting Human Carcinogens.- Indices for Identification of Genotoxic and Epigenetic Carcinogens in Cell Culture.- Enzymes.- Chairmen's Overview on Enzyme Markers.- Aryl Hydrocarbon Hydroxylase Activity 'of Mice and Humans'.- Gamma-Glutamyl Transpeptidase Expression in Neoplasia and Development.- Ornithine Decarboxylase: Alterations in Carcinogenesis.- Human Tumors: Enzyme Activities and Isozyme Profiles.- Enzyme and Isoenzyme Patterns as Potential Markers of Neoplasia in Breast Tissue.- Oncofetal Antigens and Hormones.- Chairmen's Overview on Oncodevelopmental Markers.- Alphafetoprotein as a Marker for Early Events and Carcinoma Development During Chemical Hepatocarcinogenesis.- Human Chorionic Gonadotropin and its Subunits as Tumor Markers.- Prostaglandins and Cancer.- Monoclonal Antibodies.- Chairmen's Overview on the Use of Immunoanalytical Method for the Characterization and Quantification of DNA Components Structurally Modified by Carcinogens and Mutagens.- Immunological Approaches for the Detection of DNA Modified by Environmental Agents.- Detection of Thymine Dimers in DNA with Monoclonal Antibodies.- Immunological Studies on the Influence of Chromatin Structure on the Binding of a Chemical Carcinogen to the Genome.- High-Affinity Monoclonal Antibodies Specifically Directed Against DNA Components Structurally Modified by Alkylating N-Nitroso Compounds.- Carcinogen-Induced Modification in DNA.- Chairmen's Overview on Carcinogen-Induced Modification in DNA.- Use of Repair-Deficient Mammalian Cells for the Identification of Carcinogens.- Thymine Modifications in DNA as Markers of Radiation Exposure.- Aberrant Methylation of DNA as an Effect of Cytotoxic Agents.- Identification of Carcinogen-DNA Adducts by Immunoassays.- Viruses.- Chairman's Overview on Integration and Expression of the Polyoma Virus Oncogenes in Transformed Cells.- Activation of Cellular onc (c-onc) Genes: A Common Pathway for Oncogenesis.- Hepatitis B Virus as an Environmental Carcinogen.- Roundtable Discussion.- Research Needs on the Use of Tumor Markers in the Identification of Chemical Carcinogens.- Posters.- The Polypeptides of the Cytosol of Hepatocyte Nodules May Exhibit a Unique Electrophoretic Pattern.- Rat Alloantigens as Cellular Markers for Hepatocytes in Genotypic Mosaic Livers During Chemically Induced Hepatocarcinogenesis.- Metabolic Considerations in the Toxicity and Mutagenicity of the Nitronaphthalenes.- Detection and Identification of Common Oncofetal Antigens on In Vitro Transformed Mouse Fibroblasts.- Inhibition of Metabolic Cooperation Between Cultured Mammalian Cells by Selected Tumor Promoters, Chemical Carcinogens, and Other Compounds.- A Rapid In Vitro Assay for Detecting Phorbol Ester-like Tumor Promoters.- Induction of Endogenous Murine Retrovirus by Chemical Carcinogens.- In Utero Induction of Sister Chromatid Exchanges to Detect Transplacental Carcinogens.- Evaluation of Known Genotoxic Agents and 9 -Tetrahydrocannabinol for SCE Induction by the Intraperitoneal 5-Bromo-2'-Deoxyuridine Infusion Technique for Sis.

Seller Inventory # 9781461337928

Bibliographic Details

• Title: Application of Biological Markers to Carcinogen Testing
• Publisher: Springer US
• Publication Date: 2011
• Language: English
• ISBN 10: 1461337925
• ISBN 13: 9781461337928
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 244W x 170H x 29D millimeters 244 millimeters width by 170 millimeters height by 29 millimeters depth
• Weight: 907 grams

About this title

Synopsis

"A Death at Camp David" is a political thriller set against the backdrop of the election of a woman for president of the United States.
Dr. Bob Kramer, a forensic toxicologist with the air and suave demeanor of a James Bond, is recruited to identify the cause of a woman's death. The body was found on the grounds of Camp David the morning after a White House–sponsored Fourth of July celebration. The woman attended the event as an impostor, a result of political dirty tricks. Morgan Baker, an obese and unkempt private investigator from Louisiana, is hired to sleuth and assist in the investigation. Unbeknownst to the president, her husband and the vice president, Eric Bunting, are lovers and are implicated in the death. But who was that woman? How did she die? Was she a woman? How will her death affect the upcoming presidential election of Jessica Worthing, who is running in her own right after the sudden death of her male predecessor, Leslie Breckenridge?