Axonal Branching And Recovery of Coordinated Muscle Activity After Transsection of the Facial Nerve in Adult Rats

Angelov, D. N./ Guntinas-Lichius, O./ Wewetzer, K./ Neiss, Wolfram Friedrich/ Streppel, M.

ISBN 10: 3540256547 / ISBN 13: 9783540256540

Published by Springer Verlag, 2005

About this Item

1st edition. 130 pages. German language. 9.00x6.00x0.50 inches. In Stock.

Seller Inventory # x-3540256547

Bibliographic Details

• Title: Axonal Branching And Recovery of Coordinated Muscle Activity After Transsection of the Facial Nerve in Adult Rats
• Publisher: Springer Verlag
• Publication Date: 2005
• Language: English
• ISBN 10: 3540256547
• ISBN 13: 9783540256540
• Binding: Paperback
• Condition: Brand New
• Weight: 0.3 kilograms

About this title

Synopsis

Facial nerve surgery inevitably leads to partial pareses, abnormally associated movements and pathologically altered reflexes. The reason for this "post-paralytic syndrome" is the misdirected reinnervation of targets, which consists of two major components. First, due to malfunctioning axonal guidance, a muscle gets reinnervated by a "foreign" axon, that has been misrouted along a "wrong" fascicle. Second, the supernumerary collateral branches emerging from all transected axons simultaneously innervate antagonistic muscles and cause severe impairment of their coordinated activity. Since it is hardly possible to influence the first major component and improve the guidance of several thousands axons, the authors concentrated on the second major component and tried to reduce the collateral axonal branching.

From the Back Cover

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