Basic Molecular and Cell Biology

Contents: Preface. 1. Molecular and cell biology in clinical medicine: introduction/David J. Weatherall. 2. Methods in molecular medicine/Paul M. Brickell. 3. The polymerase chain reaction: a tool for molecular medicine/A.F. Markham. 4. An introduction to cells/Lewis Wolpert. 5. Stem cells in normal growth and disease/B.R. Clark and T.M. Dexter. 6. Cell reproduction/Paul Nurse. 7. Apoptosis (programmed cell death)/Mary KL Collins. 8. Cell to cell and cell to matrix adhesion/DR Garrod. 9. How do receptors at the cell surface transmit signals to the cell interior?/Robert H. Michell. 10. Membrane traffic, from cell to clinic/John Armstrong. 11. Cytoskeleton and disease/Durward Lawson. 12. The cell nucleus/R.A. Laskey. 13. Gene regulation and transcription factors/David S. Latchman. 14. Genes and cancer/Richard G Vile, Myra O McClure and Jonathan N. Weber. 15. Human congenital malformations: insights from molecular genetics/Paul M. Brickell. 16. Molecular genetics of common diseases/Ian NM Day. 17. Impact of molecular biology on clinical genetics/William Reardon. 18. Monoclonal antibodies in medicine/Robert E. Hawkins, Kerry A. Chester, Meirion B. Llewelyn, and Stephen J. Russell. 19. Production and use of therapeutic agents/CR Bebbington and NH Carey. 20. Gene therapy/Heung Chong and Richard G Vile. Index. "This third, fully revised edition brings the reader right up to date with the recent advances made in the study of disease at the molecular and cellular level, and examines the exciting new possibilities for treatment. Leaders in the field explain the techniques of molecular and cell biology, their applications in a wide range of specialities, and their implications for medicine. Subjects covered include: Methods used in molecular medicine. The polymerase chain reaction. Recent advances in cell biology. Molecular genetics of common diseases. The role of molecular biology in diagnosis. Gene therapy. Its clear and straightforward style will give doctors, medical students and researchers valuable insight into molecular medicine and its applications.".…