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This is the story of how three men won the Nobel Prize for their research on the humble nematode worm C. elegans; how their extraordinary discovery led to the sequencing of the human genome; how a global multibillion-dollar industry was born; and how the mysteries of life were revealed in a tiny, brainless worm.
In 1998 the nematode worm―perhaps the most intensively studied animal on earth―was the first multicellular organism ever to have its genome sequenced and its DNA mapped and read. "When we understand the worm, we will understand life," predicted John Sulston, one of the three Nobel laureates, and his prediction proved astonishingly accurate. Four years later, the research that led to this extraordinary event garnered three scientists a Nobel Prize. Along with Robert Horvitz and Sydney Brenner, Sulston discovered the phenomenon of programmed cell death in the worm, an essential concept that explains how biological development occurs in animal life and, as Horvitz later showed, how it occurs in human life. C. elegans is about as simple as an animal can be, but understanding its genetic organization is helping to reveal the mechanisms of life and, by extension, the mechanisms of our own lives. In the Beginning Was the Worm shows that in order to unlock the secrets of the human genome we must first understand the worm.
But this story is about more than just the worm. It is about how an eccentric group of impassioned scientists toiled in near anonymity for years, driven only by a deep passion for knowledge and scientific discovery. It is the story of countless hours of research, immense ambition, and one of the greatest discoveries in human history.
About the Author: Andrew Brown is a journalist who writes extensively for the Guardian, the Independent, and the Daily Mail. He is the author of two acclaimed books: Watching the Detectives and The Darwin Wars.
Title: In the Beginning Was the Worm: Finding the ...
Publisher: Columbia University Press
Publication Date: 2003
Binding: Hardback
Condition: New
Seller: Once Upon A Time Books, Siloam Springs, AR, U.S.A.
hardcover. Condition: Acceptable. This is a used book. It may contain highlighting/underlining and/or the book may show heavier signs of wear . It may also be ex-library or without dustjacket. This is a used book. It may contain highlighting/underlining and/or the book may show heavier signs of wear . It may also be ex-library or without dustjacket. Seller Inventory # mon0000803815
Quantity: 1 available
Seller: Windows Booksellers, Eugene, OR, U.S.A.
Hardcover, no dust jacket. Light and infrequent pencil markings throughout. Boards are worn and scuffed. Some paint spots on outer edge of boards. 244 pages. 244 pp. Seller Inventory # 442841
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Seller: Better World Books, Mishawaka, IN, U.S.A.
Condition: Good. 1st Edition. Former library book; may include library markings. Used book that is in clean, average condition without any missing pages. Seller Inventory # 352783-75
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Seller: ThriftBooks-Atlanta, AUSTELL, GA, U.S.A.
Hardcover. Condition: As New. No Jacket. Pages are clean and are not marred by notes or folds of any kind. ~ ThriftBooks: Read More, Spend Less 0.95. Seller Inventory # G0231131461I2N00
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Seller: FITZ BOOKS AND WAFFLES, Buffalo, NY, U.S.A.
Hardcover. Condition: Very Good. Dust Jacket Condition: Good. 1st Edition. Remainder and price marking, otherwise an unmarked and undamaged copy. Intact dust jacket, not ex-library. Seller Inventory # ABE-1722116626833
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Seller: Chequamegon Books, Washburn, WI, U.S.A.
Hardcover. Condition: Fine in Near Fine dust jacket. Sticker neatly removed from DJ spine; light bumping along DJ edges. ; The story of three men who won the Nobel Prize for their research on the humble nematode worn and how their discovery led to the sequencing of the human genome. ; 5 7/8 x 8 1/2"; 244 pages. Seller Inventory # 114977
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Seller: Best Price, Torrance, CA, U.S.A.
Condition: New. SUPER FAST SHIPPING. Seller Inventory # 9780231131469
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Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
Condition: New. Seller Inventory # ABLIING23Feb2215580075837
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Seller: Rarewaves USA, OSWEGO, IL, U.S.A.
Hardback. Condition: New. This is the story of how three men won the Nobel Prize for their research on the humble nematode worm C. elegans; how their extraordinary discovery led to the sequencing of the human genome; how a global multibillion-dollar industry was born; and how the mysteries of life were revealed in a tiny, brainless worm. In 1998 the nematode worm-perhaps the most intensively studied animal on earth-was the first multicellular organism ever to have its genome sequenced and its DNA mapped and read. "When we understand the worm, we will understand life," predicted John Sulston, one of the three Nobel laureates, and his prediction proved astonishingly accurate. Four years later, the research that led to this extraordinary event garnered three scientists a Nobel Prize. Along with Robert Horvitz and Sydney Brenner, Sulston discovered the phenomenon of programmed cell death in the worm, an essential concept that explains how biological development occurs in animal life and, as Horvitz later showed, how it occurs in human life. C. elegans is about as simple as an animal can be, but understanding its genetic organization is helping to reveal the mechanisms of life and, by extension, the mechanisms of our own lives.In the Beginning Was the Worm shows that in order to unlock the secrets of the human genome we must first understand the worm. But this story is about more than just the worm. It is about how an eccentric group of impassioned scientists toiled in near anonymity for years, driven only by a deep passion for knowledge and scientific discovery. It is the story of countless hours of research, immense ambition, and one of the greatest discoveries in human history. Seller Inventory # LU-9780231131469
Quantity: Over 20 available
Seller: Rarewaves USA United, OSWEGO, IL, U.S.A.
Hardback. Condition: New. This is the story of how three men won the Nobel Prize for their research on the humble nematode worm C. elegans; how their extraordinary discovery led to the sequencing of the human genome; how a global multibillion-dollar industry was born; and how the mysteries of life were revealed in a tiny, brainless worm. In 1998 the nematode worm-perhaps the most intensively studied animal on earth-was the first multicellular organism ever to have its genome sequenced and its DNA mapped and read. "When we understand the worm, we will understand life," predicted John Sulston, one of the three Nobel laureates, and his prediction proved astonishingly accurate. Four years later, the research that led to this extraordinary event garnered three scientists a Nobel Prize. Along with Robert Horvitz and Sydney Brenner, Sulston discovered the phenomenon of programmed cell death in the worm, an essential concept that explains how biological development occurs in animal life and, as Horvitz later showed, how it occurs in human life. C. elegans is about as simple as an animal can be, but understanding its genetic organization is helping to reveal the mechanisms of life and, by extension, the mechanisms of our own lives.In the Beginning Was the Worm shows that in order to unlock the secrets of the human genome we must first understand the worm. But this story is about more than just the worm. It is about how an eccentric group of impassioned scientists toiled in near anonymity for years, driven only by a deep passion for knowledge and scientific discovery. It is the story of countless hours of research, immense ambition, and one of the greatest discoveries in human history. Seller Inventory # LU-9780231131469
Quantity: Over 20 available