Biliary Lithiasis: Basic Science, Current Diagnosis and Management

The first laparoscopic cholecystectomy, performed by Prof. Philippe Mouret in 1987 and described by himself in the first chapter of this book, was an event that revolutionized surgery in the past few decades. Although the majority of surgeons today are unfamiliar with the his- ry of early minimally invasive surgery developments, it is important to realize that the advent of laparoscopy led not only to new surgical te- niques, but also to a change in the doctrine of medical care, by streng- ening the concept of minimal invasiveness. This is particularly the case for biliary lithiasis, for which laparoscopy has provided major benefits in terms of both diagnosis and surgical tre- ment. However, our understanding of the etiology of this disease, as well as the availability of effective medical therapies, have remained subst- tially unchanged over time. The application of the innovative approach has not been, in routine practice, without problems: between 1990 and 2000, the rate of serious complications from laparoscopic cholecystectomy were four times higher than those observed with open surgery. Even initial attempts at lapa- scopic treatment of biliary common bile duct stones resulted in excessive complications and associated medico-legal problems. Nonetheless, today, most indications have been stated, techniques have been standardized, and a new aspect to the treatment of biliary lithiasis has appeared.

The book provides an overview on biliary lithiasis and all its clinical pictures, twenty years after the first laparoscopic cholecystectomy. The gallbladder, the main bile duct and intra-hepatic stones, in their uncomplicated and complicated forms are illustrated. Chapters are focused on basic science, epidemiology, diagnostic and therapeutic approaches to biliary lithiasis. The different diagnostic procedures described include  invasive and noninvasive imaging,  and treatment options take into consideration medical treatment, open and minimally invasive surgery, endoscopic and percutaneous approaches, both individually and as combined procedures. 

The book's content is not limited to the most commonly used therapeutic approaches reported in the literature, but also addresses new and innovative therapeutic strategies for biliary lithiasis.

Thanks to its comprehensive approach, this volume will be of interest not only for GPs amd specialists in this field, but also to residents and other health professional of different disciplines.