Biochemistry of microbial degradation

Colin Ratledge

ISBN 10: 9401047383 / ISBN 13: 9789401047388

Published by Springer Netherlands, Springer Netherlands, 2012

About this Item

Druck auf Anfrage Neuware - Printed after ordering - Life on the planet depends on microbial activity. The recycling of carbon, nitrogen, sulphur, oxygen, phosphate and all the other elements that constitute living matter are continuously in flux: microorganisms participate in key steps in these processes and without them life would cease within a few short years. The comparatively recent advent of man-made chemicals has now challenged the environment: where degradation does not occur, accumulation must perforce take place. Surprisingly though, even the most recalcitrant of molecules are gradually broken down and very few materials are truly impervious to microbial attack. Microorganisms, by their rapid growth rates, have the most rapid turn-over of their DNA of all living cells. Consequently they can evolve altered genes and therefore produce novel enzymes for handling 'foreign' compounds - the xenobiotics - in a manner not seen with such effect in other organisms. Evolution, with the production of micro-organisms able to degrade molecules hitherto intractable to breakdown, is therefore a continuing event. Now, through the agency of genetic manipulation, it is possible to accelerate this process of natural evolution in a very directed manner. The time-scale before a new microorganism emerges that can utilize a recalcitrant molecule has now been considerably shortened by the application of well-understood genetic principles into microbiology. However, before these principles can be successfully used, it is essential that we understand the mechanism by which molecules are degraded, otherwise we shall not know where best to direct these efforts.

Seller Inventory # 9789401047388

Bibliographic Details

• Title: Biochemistry of microbial degradation
• Publisher: Springer Netherlands, Springer Netherlands
• Publication Date: 2012
• Language: English
• ISBN 10: 9401047383
• ISBN 13: 9789401047388
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 240W x 160H x 33D millimeters 240 millimeters width by 160 millimeters height by 33 millimeters depth
• Weight: 969 grams

About this title

Synopsis

Life on the planet depends on microbial activity. The recycling of carbon, nitrogen, sulphur, oxygen, phosphate and all the other elements that constitute living matter are continuously in flux: microorganisms participate in key steps in these processes and without them life would cease within a few short years. The comparatively recent advent of man-made chemicals has now challenged the environment: where degradation does not occur, accumulation must perforce take place. Surprisingly though, even the most recalcitrant of molecules are gradually broken down and very few materials are truly impervious to microbial attack. Microorganisms, by their rapid growth rates, have the most rapid turn-over of their DNA of all living cells. Consequently they can evolve altered genes and therefore produce novel enzymes for handling "foreign" compounds - the xenobiotics - in a manner not seen with such effect in other organisms. Evolution, with the production of micro-organisms able to degrade molecules hitherto intractable to breakdown, is therefore a continuing event. Now, through the agency of genetic manipulation, it is possible to accelerate this process of natural evolution in a very directed manner. The time-scale before a new microorganism emerges that can utilize a recalcitrant molecule has now been considerably shortened by the application of well-understood genetic principles into microbiology. However, before these principles can be successfully used, it is essential that we understand the mechanism by which molecules are degraded, otherwise we shall not know where best to direct these efforts.

About the Author

Colin Ratledge is Emeritus Professor in the Department of Biological Sciences at the University of Hull where he has been teaching and researching for nearly 40 years. He has served on almost all the major biotechnology committees in the UK, including Chairperson of the Biological and Biotechnology Research Council. He also acts as a consultant to many industrial companies in the UK, Europe and the USA.