The first volume offers comprehensive information about the technology of instruments and the art of applying them in experimental settings. For example, it contains:
- an overview of the ultrastructure and biochemistry of the epidermal barrier
- an explanation of the instruments for measuring transepidermal water loss and epidermal moisture
- guidelines for standardization of measurements and communication of results
- review of current knowledge on epidermal water and transepidermal water loss in health and disease
- instruction by experienced investigators about how to perform product testing with these instruments

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