Biological Applications of Nanoparticles

This textbook for graduate and postgraduate students provides comprehensive applications of nanoparticles in medicine, agriculture, and environmental sciences. The initial chapter covers basic topics related to types, synthesis, structure, and properties of various nanoparticles. It further discusses the wide range of applications of nanoparticles in medicine, agriculture, and the environment. The book presents nano-electronic biosensors that are used to diagnose and monitor the progression of human diseases. It summarizes the opportunities and challenges of nanotechnology in the agriculture and food sector highlighting the scientific, technical, regulatory, safety, and societal impacts.

Additionally, it illustrates the applications of nanotechnology in the field of aquaculture medicine, bioinformatics and food technology. The textbook examines the development and administration  of nano-medicines , their applications, advantages, and limitations for the treatmentand prophylaxis of a broad range of diseases. Lastly, the textbook explores the recent advances in the field of nanobusiness and nanotechnology issues in intellectual property management( IPR).

Dr. Biplab Sarkar is currently working as Principal Scientist(Nanobiotechnology) at ICAR-Indian Institute of Agricultural Biotechnology, Ranchi, Jharkhand. His group is focusing nanotechnology driven research for agricultural benefits. He   has published more than forty-five international papers, and worked at ‘Centre of excellence (COE)’, Nanotech., AIT, Thailand on nanoparticle synthesis and characterization. He executed two DST and two ICAR institute funded projects on nano-formulations and nano-encapsulation for agricultural use. His group developed novel methods of formulating   anti-bacterial nanosilver from rohu waste-tissues (Patent a.-3255/Mum/2012) and nanocomposite hydrogel for wound healing (Patent a.-9172/2019-KOL). First time, he reported the growth promoting role of nanosilver, unleashed the dose dependent molecular activity of magnesium and iron nanoparticles in zebra fish, and framed the futuristic application of nanoscale selenium and zinc. He also worked on nano-zeolite, nano-hydrogel, nanoliposomes for use in farming sector.

Prof. Avinash Sonawane is working as professor at IIT-Indore. He is elected  as the fellow of Royal Society of Biology (FRSB), UK; Humboldt Fellow, Germany; SwissNational Science Fellow: Switzerland; EMBO Fellow:Germany; JSPS Fellow:Japan. He has published more than fifty international research articles and four patents. His group has identified several novel Mycobacterium tuberculosis virulence and antigenic determinants that subvert host innate immune responses such as autophagy, oxidative stress, peroxisome biosynthesis, host antimicrobial peptide synthesis, genomic stability and T-cell activation using mice and zebrafish infection models. They demonstrated that nanoparticle encapsulated anti-TB drug delivery through polymer, chitosan etc. admixed with metal and metal oxide nanoparticles can exhibited targeted delivery and higher efficacy in the animal models.