Biophysics of Molecular Chaperones: Function, Mechanisms and Client Protein Interactions

Hiller, Sebastian (Editor)/ Liu, Maili (Editor)/ He, Lichun (Editor)

ISBN 10: 1839162821 / ISBN 13: 9781839162824

Published by Royal Society of Chemistry, 2023

About this Item

402 pages. 9.21x6.14x0.94 inches. In Stock.

Seller Inventory # x-1839162821

Bibliographic Details

• Title: Biophysics of Molecular Chaperones: Function, Mechanisms and Client Protein Interactions
• Publisher: Royal Society of Chemistry
• Publication Date: 2023
• Language: English
• ISBN 10: 1839162821
• ISBN 13: 9781839162824
• Binding: Hardcover
• Condition: Brand New
• Weight: 0.77 kilograms

About this title

Synopsis

Molecular chaperones are critical to control protein quality in all living cells. Understanding chaperone function at the atomic level, and in particular its mode of interaction with client proteins, is crucial to understanding the fundamental roles chaperones play in biology. This book fills a gap in the literature by comprehensively summarizing and discussing new advanced experimental techniques for their analysis. Providing a comprehensive overview of advanced biophysical methods for the characterization of molecular mechanisms of molecular chaperones, the majority of the contributions are NMR methodology. This is the method of choice for atomic resolution studies of such systems. Additional notable biophysical approaches are considered to present all relevant current developments in exploring chaperone function and the transient and dynamic interactions with their client proteins.

The book is targeted at both current practitioners of structural biology and biophysical chemistry and scientists who are interested in entering the field. It could be useful for graduate students as supplementary reading.