Functional magnetic resonance imaging (fMRI) measures quick, tiny metabolic changes that take place in the brain, providing the most sensitive method currently available for identifying, investigating, and monitoring brain tumors, stroke, and chronic disorders of the nervous system like multiple sclerosis, and brain abnormalities related to dementia or seizures. This overview explains the principles of fMRI, scanning methodlogies, experimental design and data analysis, and outlines challenges and limitations of fMRI. It also provides a detailed neuroanatomic atlas, and describes clinical applications of fMRI in cognitive, sensory, and motor cases, translating research into clinical application.

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BOLD fMRI: A Guide for Neuroscientists is a compilation of key chapters selected by the editors to present neuroscientists with a comprehensive introduction to the basic principles of BOLD fMRI and its applications in cognitive neuroscience. This comprehensive book introduces important topics in BOLD fMRI such as scanning methodologies, experimental design and data analysis, and its challenges and limitations. Clinical applications of functional imaging are included in chapters on brain mapping in cognitive neuroscience, memory in aging and dementia, language systems, and the Wada test. Also included is a full-color neuroanatomical atlas of the basic motor, sensory, and cognitive activation sites that are discussed throughout the book. With contributions from internationally recognized neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists, this volume will appeal to all neuroscientists seeking a concise introduction to the fundamentals of BOLD fMRI.

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