Bone Scanning in Clinical Practice

Ignac Fogelman

ISBN 10: 1447114094 / ISBN 13: 9781447114093

Published by Springer, Springer Jan 2012, 2012

About this Item

This item is printed on demand - Print on Demand Titel. Neuware -The most frequently requested investigation in any nuclear medicine department remains the technetium-99m (99mTc)-labelled diphosphonate bone scan. Despite rapid advances in all imaging modalities. there has been no serious challenge to the role of bone scanning in the evaluation of the skeleton. The main reason for this is the exquisite sensitivity of the bone scan for lesion detection. combined with clear visualisation of the whole skeleton. In recent years several new diphosphonate agents have become available with claims for superior imaging of the skeleton. Essentially. they all have higher affinity for bone. thus allowing the normal skeleton to be visualised all the more clearly. However. as will be dis cussed. this may occur at some cost to the principal role of bone scanning. lesion detection. The major strength of nuclear medicine is its ability to provide functional and physiological information. With bone scanning this leads to high sensitivity for focal disease if there has been any disturbance of skeletal metabolism. However. in many other clinical situations. and particularly in metabolic bone disease. more generalised alteration in skeletal turnover may occur. and quantitation of diphosphonate uptake by the skeleton can provide valuable clinical information.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 280 pp. Englisch.

Seller Inventory # 9781447114093

Bibliographic Details

• Title: Bone Scanning in Clinical Practice
• Publisher: Springer, Springer Jan 2012
• Publication Date: 2012
• Language: English
• ISBN 10: 1447114094
• ISBN 13: 9781447114093
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 280W x 210H x 16D millimeters 280 millimeters width by 210 millimeters height by 16 millimeters depth
• Weight: 692 grams

About this title

Synopsis

The most frequently requested investigation in any nuclear medicine department remains the technetium-99m (99mTc)-labelled diphosphonate bone scan. Despite rapid advances in all imaging modalities. there has been no serious challenge to the role of bone scanning in the evaluation of the skeleton. The main reason for this is the exquisite sensitivity of the bone scan for lesion detection. combined with clear visualisation of the whole skeleton. In recent years several new diphosphonate agents have become available with claims for superior imaging of the skeleton. Essentially. they all have higher affinity for bone. thus allowing the normal skeleton to be visualised all the more clearly. However. as will be dis­ cussed. this may occur at some cost to the principal role of bone scanning. lesion detection. The major strength of nuclear medicine is its ability to provide functional and physiological information. With bone scanning this leads to high sensitivity for focal disease if there has been any disturbance of skeletal metabolism. However. in many other clinical situations. and particularly in metabolic bone disease. more generalised alteration in skeletal turnover may occur. and quantitation of diphosphonate uptake by the skeleton can provide valuable clinical information.