Brain Development | Roles of Transient Neurons in Corpus Callosum Formation and Guidance

Mathieu Niquille

ISBN 10: 3659218499 / ISBN 13: 9783659218491

Published by LAP LAMBERT Academic Publishing, 2012

About this Item

Brain Development | Roles of Transient Neurons in Corpus Callosum Formation and Guidance | Mathieu Niquille | Taschenbuch | 120 S. | Englisch | 2012 | LAP LAMBERT Academic Publishing | EAN 9783659218491 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Seller Inventory # 106305655

Bibliographic Details

• Title: Brain Development | Roles of Transient Neurons in Corpus Callosum Formation and Guidance
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2012
• Language: English
• ISBN 10: 3659218499
• ISBN 13: 9783659218491
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 8D millimeters 220 millimeters width by 150 millimeters height by 8 millimeters depth
• Weight: 197 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

The brain is a main center for control over the other organs in all vertebrate. It is responsible for higher-order functions like processing environmental stimuli or language and it is divided in two hemispheres. In order to achieve such tasks, the right and left sides need to be connected and the corpus callosum is the major bridge (over 200 mio. of axons) channeling and coordinating information between these two hemispheres. Previous works have shown that glial cells (non-neuronal brain cells) found at the midline of the brain are essential for guiding the projections from one side to the other side. We found that two populations of neuronal cells are also required for the proper formation of the corpus callosum and for the guidance of interhemispheric axons during embryonic development. Similar mechanisms could occur in humans and observations of human pathologies with defects in corpus callosum formation suggest that these neurons could be involved. This work thus gives new insights into how neurons together with their glial partners have the ability to shape the corpus callosum, a potential process for guidance in other brain regions.

About the Author

Mathieu Niquille has achieved a Phd degree in Neurosciences in 2011 in the field of Developmental Neurobiology. His work focused on embryonic brain wiring and guidance and was the matter of a first author publication in PLOS Biology and a co-author publication in PLOS Genetics. He has then extended its researchs in Psychatric Neurobiology.