This challenging 2001 book reviews modern neurotherapeutics from the point of view of drug targeting. Num Pages: 376 pages, black & white illustrations. BIC Classification: MJN; MMGW. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 20. Weight in Grams: 600. . 2010. Reissue. paperback. . . . . Books ship from the US and Ireland.

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Bibliographic Details

Title: Brain Drug Targeting: The Future of Brain Drug Development
Publisher: Cambridge University Press
Publication Date: 2010
Language: English
ISBN 10: 0521154464
ISBN 13: 9780521154468
Binding: Soft cover
Condition: New

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Synopsis

In this innovative and challenging book, William Pardridge, a world leader in the study of the blood-brain barrier and its clinical implications, argues that brain drug development has been restricted by the failure of adequate brain drug targeting. This is an increasingly urgent problem as developments in genomics lead to new generations of therapeutic macromolecules. The author reviews the field of neurotherapeutics from the point of view of drug targeting. He surveys the scientific and clinical basis of drug delivery across biological membranes, including topics such as genetically engineered trojan horses for drug targeting, antisense neurotherapeutics, and gene therapy of brain disorders. At a time when there are few significant new drug treatments in prospect for common neurological diseases, this authoritative review will encourage a wide range of clinicians and neuroscientists to reexamine the development and use of drugs in treating disorders of the central nervous system.

Book Description

Brain drug development has been restricted by the failure of adequate brain drug targeting, an increasingly urgent problem as developments in genomics lead to new generations of therapeutic macromolecules. This challenging book reviews the field of neurotherapeutics from the point of view of drug targeting, surveying the scientific and clinical basis of drug delivery across biological membranes. It will encourage a wide range of clinicians and neuroscientist s to reexamine the development and use of drugs in treating disorders of the central nervous system.

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