Brain Imaging Using PET

Discussing not only PET technique and instrumentation, but new developments in a broad range of fields such as kinetics, enzyme/neurotransmitter transport, language acquisition, and neuropathology, Brain Imaging Using PET will appeal to both PET experts and non-PET users in many branches of neuroscience. The authors offer an invaluable analysis of brain imaging and techniques, providing everything from the foundations to the practical applications of the modern techniques used in PET.

Positron Emission Tomography (PET) is a powerful, non-invasive tool used to study the biochemistry and physiology of the working brain. This imaging technique measures the metabolic activity and neurotransmission of nerve cells, yielding a quantified, visual analysis of the cellular and physiological mechanisms underlying brain function both in humans and in animals.

Written by international experts in the field, Brain Imaging with PET follows current developments including instrumentation, quantification, image analysis, tracer kinetics, parametric imaging and other methodological designs. It also focuses on the physiology of the working brain from the biochemical level of neurotransmitter release to the global analysis of entire neuronal systems. It addresses brain functioning in normal individuals and in patients with both acquired and idiopathic disorders.

Key Features
* Head motion correction
* Tricks for PET imaging of monkeys and other animals
* Parametric images by quantification without arterial blood sampling
* Measurement of endogenous dopamine release
* Imaging acetylcholine esterase activity in Alzheimer patients
* Dopaminergic functions in Parkinson patients and animal models
* New tracers for PET imaging of NK1, sigma-1 and other receptors
* Application of Bayesian, wavelet, cluster and other math techniques