CARDIOPROTECTIVE ACTIVITY OF GLYCITEIN IN RATS: EVALUATION OF CARDIOPROTECTIVE ACTIVITY OF GLYCITEIN ON ISOPROTERENOL INDUCED MYOCARDIAL INJURY IN RATS

Ramachandran, Vadivelan, Sharma, Khushi, S, Sudeep

ISBN 10: 6207450779 / ISBN 13: 9786207450770

Published by LAP LAMBERT Academic Publishing, 2023

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Bibliographic Details

• Title: CARDIOPROTECTIVE ACTIVITY OF GLYCITEIN IN RATS: EVALUATION OF CARDIOPROTECTIVE ACTIVITY OF GLYCITEIN ON ISOPROTERENOL INDUCED MYOCARDIAL INJURY IN RATS
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2023
• Language: English
• ISBN 10: 6207450779
• ISBN 13: 9786207450770
• Binding: paperback
• Condition: New
• Book Type: book

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Synopsis

Myocardial Infarction (MI) is a cardiomyocyte death due to a prolonged ischemia resulting from an acute imbalance between oxygen supply and demand. MI is a major public health concern and is one of the primary causes of mortality worldwide. The present study is to evaluate the effect of Glycitein in isoproterenol induced rat model. Electro cardiac parameter (ECG, heart rate), cardiac markers (CK-MB and LDH) and antioxidant parameter (LPO) were analyzed to investigate the activity of Glycitein in the treatment of myocardial infarction. The treatment with Glycitein could significantly reduce the heart weight, ST elevation, cardiac markers (CK-MB) and lipid peroxidation to discuss its cardioprotective action in contradiction of isoproterenol induced myocardial damage. Hence, the findings states that the administration of Glycitein is an effective treatment for myocardial infarction.