CARDIOPROTECTIVE ACTIVITY OF GLYCITEIN IN RATS | EVALUATION OF CARDIOPROTECTIVE ACTIVITY OF GLYCITEIN ON ISOPROTERENOL INDUCED MYOCARDIAL INJURY IN RATS

Publisher

LAP LAMBERT Academic Publishing

Publication Date

2023

Language

English

ISBN 10

6207450779

ISBN 13

9786207450770

Binding

Taschenbuch

Condition

Neu

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Weight

107 grams

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Synopsis

Myocardial Infarction (MI) is a cardiomyocyte death due to a prolonged ischemia resulting from an acute imbalance between oxygen supply and demand. MI is a major public health concern and is one of the primary causes of mortality worldwide. The present study is to evaluate the effect of Glycitein in isoproterenol induced rat model. Electro cardiac parameter (ECG, heart rate), cardiac markers (CK-MB and LDH) and antioxidant parameter (LPO) were analyzed to investigate the activity of Glycitein in the treatment of myocardial infarction. The treatment with Glycitein could significantly reduce the heart weight, ST elevation, cardiac markers (CK-MB) and lipid peroxidation to discuss its cardioprotective action in contradiction of isoproterenol induced myocardial damage. Hence, the findings states that the administration of Glycitein is an effective treatment for myocardial infarction.

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