Title: CONCEPTION D?UN COMPRIME GENERIQUE DE PARACETAMOL 500MG: OPTIMISATION DE LA FORMULE, MISE EN ?UVRE TECHNOLOGIQUE SIMPLIFIEE (Omn.Univ.Europ.) (French Edition)
Publisher: �ditions universitaires europ�ennes
Publication Date: 2010
Language: French
ISBN 10: 6131521379
ISBN 13: 9786131521379
Binding: Soft cover
Condition: New
Weight: 234 grams

About this title

Synopsis

L’objectif principal de ce travail est de mettre en pratique une m�thodologie d’optimisation et de simplification du couple formule - proc�d� dans le cadre de la production d’un comprim� g�n�rique. Le cas d’�cole choisi est un comprim� contenant 500 mg de parac�tamol. Il s’agit d’un antalgique et antipyr�tique bien connu, des plus utilis�s au monde. 57 sp�cialit�s list�es dans le Vidal 2005, tous dosages et toutes formes pharmaceutiques confondus, contiennent du parac�tamol. La forte quantit� de parac�tamol dans un comprim� impose une optimisation pr�cise quant aux choix des excipients, ceux-ci �tant automatiquement minoritaires dans la formule. La finalit� �tant d’obtenir un comprim� g�n�rique, la premi�re �tape de ce travail sera la caract�risation de comprim�s commerciaux, choisis comme r�f�rence.

About the Author

N� le 05/09/1980 � Saint R�my (71).Dipl�m� du titre de Docteur en Pharmacie � la facult� dePharmacie de Dijon (21) en 2006

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