Calcium Entry Channels in Non-excitable Cells

Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.

Ashot Kozak is Associate Professor of Neuroscience, Cell Biology and Physiology in the Department of Biological Sciences at Wright State University in Dayton, Ohio. He received his PhD from Mount Sinai School of Medicine and did a postdoc at the University of California, Irvine. His research focuses upon cation channels expressed in leukocytes; Transient Receptor Potential (TRP) channels; ion channels involved in nociception.