This two-volume set provides information on all major aspects of cancer biology. The 102 contributions discuss the molecular basis of cell and tissue organization, the pathways by which cells disregard signals to stop proliferating and signals to differentiate, the capacity for sustained proliferation, evasion of apoptosis, and the ability to invade and induce angiogenesis; the causation and prevention of cancer; systemic oncology; a review of the many models used to dissect the basic processes common to many cancers, as well as organ-specific cancers and common methodologies such as tissue culture and transgenic technology; diagnostic imaging and image-guided intervention; and treatment of human cancer now and in the future as the new generation of molecular therapeutics develops. Contains many b&w and color illustrations. Edited by Malcolm Alison (medicine, Imperial College of Science, Technology and Medicine). Annotation c. Book News, Inc., Portland, OR (booknews.com)
Providing a comprehensive overview of scientific and clinical information in all major areas of cancer biology and medicine,
The Cancer Handbook stands out from existing oncology textbooks and reference works in that it bridges between the molecular biology of cancer and clinical diagnosis and treatment.
Covering a wide range of subjects - from basic cell biology to the systemic oncology of all major organs and tissues - the content of The Cancer Handbook has been organised into these major sections:
- The Molecular Basis of Cell and Tissue Organisation
- The Causation and Prevention of Cancer
- Systemic Oncology
- Pre-Clinical Models for Human Cancer
- Diagnostic Imaging and Image-guided Intervention
- The Treatment of Human Cancer
Written with an emphasis on clarity of style, each chapter includes numerous tables and illustrations prepared specifically for the book. Added to this are detailed colour plate sections in each volume. Each chapter concludes with a list of key references and a bibliography of recommended further reading. Extensive cross-references allow for comparisons between experimental research and treatment. A comprehensive glossary completes this major new resource for those who are not experts in the area.
Editor-in-Chief Malcolm Alison (Professor of Experimental Pathology, Imperial College, London) heads an eminent panel of international editors and advisors for The Handbook, which will be an indispensible resource not only for medical and life science students, but all scientists, clinicians and researchers working in the cancer field and related biomedical areas.
