Cardiac Gene Expression

. Ed(s): Zhang, Jun; Rokosh, Gregg

ISBN 10: 1588293521 / ISBN 13: 9781588293527

Published by Humana Press Inc., 2007

About this Item

Addresses various methods that researchers in the cardiac field will find useful as a reference for the development of projects and training. This work aims to provide insight and details for a comprehensive range of methods that will serve both startup and sophisticated users alike. Editor(s): Zhang, Jun; Rokosh, Gregg. Series: Methods in Molecular Biology. Num Pages: 366 pages, 65 black & white illustrations, 1 colour illustrations, 16 black & white tables, biograph. BIC Classification: MJD; PSAK1; PSD. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 25. Weight in Grams: 800. . 2007. Hardback. . . . . Books ship from the US and Ireland.

Seller Inventory # V9781588293527

Bibliographic Details

• Title: Cardiac Gene Expression
• Publisher: Humana Press Inc.
• Publication Date: 2007
• Language: English
• ISBN 10: 1588293521
• ISBN 13: 9781588293527
• Binding: Hardcover
• Condition: New

About this title

Synopsis

Cardiac Gene Expression: Methods and Protocols presents both cutting-edge and established methods for studying cardiac gene expression. The protocols provide a template for solid research, and cover the process through screening, analysis, characterization, and functional confirmation of novel genes or known genes with a new function.

Section I, Cardiac Gene Expression Profiling: The Global Perspective, discusses several different approaches to examining, identifying, and analyzing changes in transcriptome gene expression. Section II, Cardiac Gene Regulation: Gene-Specific mRNA Measurement in the Myocardium, outlines more sensitive and gene-targeted expression methods. Section III, Cardiac Gene Regulation: Promoter Characterization in the Myocardium, provides protocols for the study of underlying gene regulation mechanisms by focusing on the interaction of transcription factors with their cognate cis binding elements. Section IV, In Silico Assessment of Regulatory cis-Elements and Gene Regulation, and Section V, Cardiac Single Network Polymorphisms, emphasize new analytical approaches for deciphering the functional elements buried in the 3 billion nucleotides of the human genome and other model genomes. The concluding section, Gene Overexpression and Targeting in the Myocardium, highlights methods that facilitate overexpression or cardiac-specific targeted gene deletion.

Review

"...a timely, detailed and well edited methodss text which would be a valuable addition to any cardiovascular research laboratory." -Molecular Biotechnology