Cell-Based Assays Using iPSCs for Drug Development and Testing

Carl-Fredrik Mandenius

ISBN 10: 149399476X / ISBN 13: 9781493994762

Published by Humana Mai 2019, 2019

About this Item

This item is printed on demand - Print on Demand Titel. Neuware -The volume presents a variety of protocols that will be useful to researchers working in the field of disease modeling, drug discovery, and the cell biology of various tissues. Chapters in this book cover topics such as requirements and preconditions for using human induced pluripotent cell lines in assay development; the culture of iPSCs and iPSC-derived cardiomyocytes by bioreactor technologies; distinctions between hepatocytes, vascular endothelial cells, cardiomyocytes, renal podocytes, and neurons; and high content assays of mitochondrial function and autophagy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 280 pp. Englisch.

Seller Inventory # 9781493994762

Bibliographic Details

• Title: Cell-Based Assays Using iPSCs for Drug Development and Testing
• Publisher: Humana Mai 2019
• Publication Date: 2019
• Language: English
• ISBN 10: 149399476X
• ISBN 13: 9781493994762
• Binding: Buch
• Condition: Neu
• Dimensions: 260W x 183H x 21D millimeters 260 millimeters width by 183 millimeters height by 21 millimeters depth
• Weight: 729 grams

About this title

Synopsis

The volume presents a variety of protocols that will be useful to researchers working in the field of disease modeling, drug discovery, and the cell biology of various tissues. Chapters in this book cover topics such as requirements and preconditions for using human induced pluripotent cell lines in assay development; the culture of iPSCs and iPSC-derived cardiomyocytes by bioreactor technologies; distinctions between hepatocytes, vascular endothelial cells, cardiomyocytes, renal podocytes, and neurons; and high content assays of mitochondrial function and autophagy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and cutting-edge, Cell-Based Assay using iPSCs for Drug Development and Testing: Methods and Protocols is a valuable resource for researchers working in this important and developing field of study.