Title: Cell-Cell Junctions : A Subject Collection from Cold Spring Harbor Perspectives in Biology
Publisher: Cold Spring Harbor Laboratory Press
Publication Date: 2017
Language: English
ISBN 10: 162182151X
ISBN 13: 9781621821519
Binding: Hardcover
Edition: 2nd Edition
Condition: New

About this title

Synopsis

Neighboring cells are linked to each other by multimolecular complexes such as adherens junctions, desmosomes, and gap junctions. These complexes help maintain tissue integrity, act as barriers to permeability, reinforce cell polarity, and allow cells to communicate with each other.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology reviews our understanding of the organization, regulation, and dynamics of cell-cell junctions and the roles they play in morphogenesis, tissue homeostasis, and disease. The contributors examine the assembly and structure of different cell-cell adhesion systems, the plasticity of cell-cell junctions (e.g., during cell migration), and how the junctions act as hubs to sense and transduce various mechanical and chemical signals.

The authors also discuss the roles of cell-cell junctions in specific developmental and physiological processes, such as hearing, skeletal myogenesis, and neural circuit assembly, as well as in diseases such as cancer. This volume is therefore an indispensable reference for cell and developmental biologists, as well as anyone interested in understanding the roles of these complexes in human health and disease.

About the Author

Carien M. Niessen is CECAD Coordinator, Cell Biology of the Skin in the Faculty of Medicine at the University of Cologne.

"About this title" may belong to another edition of this title.

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