Cell Commitment and Differentiation (Paperback)

Brian Keith Hall

ISBN 10: 0521349648 / ISBN 13: 9780521349642

Published by Cambridge University Press, Cambridge, 1987

About this Item

Paperback. First published in 1987, this book is about how cells differentiate; that is it describes the way in which cells in animal and plant bodies take on their specialised fates. It has long been recognised that since all such cells retain copies of all genes, the genetic explanation for tissue differences lies in the controlled expression of restricted sets of genes. But how is the choice made and how are such restricted groups of genes activated and regulated? This book discusses these questions and describes both determination and differentiation. The mechanisms that underlie the processes are described for the embryo and in the adult. Determination may occur in adult life during regeneration, wound healing, cancer formation and in the immune and blood systems, and the possible genetic basis for the events is explored. The influence of the cell environment, the cell surface and the pericellular-extracellular matrix as mediators of external signals is discussed. First published in 1987, this book is about how cells differentiate; that is it describes the way in which cells in animal and plant bodies take on their specialised fates. The mechanisms which underlie the processes are described for the embryo and in the adult. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Seller Inventory # 9780521349642

Bibliographic Details

• Title: Cell Commitment and Differentiation (Paperback)
• Publisher: Cambridge University Press, Cambridge
• Publication Date: 1987
• Language: English
• ISBN 10: 0521349648
• ISBN 13: 9780521349642
• Binding: Paperback
• Condition: new

About this title

Synopsis

First published in 1987, this book is about how cells differentiate; that is it describes the way in which cells in animal and plant bodies take on their specialised fates. It has long been recognised that since all such cells retain copies of all genes, the genetic explanation for tissue differences lies in the controlled expression of restricted sets of genes. But how is the choice made and how are such restricted groups of genes activated and regulated? This book discusses these questions and describes both determination and differentiation. The mechanisms that underlie the processes are described for the embryo and in the adult. Determination may occur in adult life during regeneration, wound healing, cancer formation and in the immune and blood systems, and the possible genetic basis for the events is explored. The influence of the cell environment, the cell surface and the pericellular-extracellular matrix as mediators of external signals is discussed.

Book Description

First published in 1987, this book is about how cells differentiate; that is it describes the way in which cells in animal and plant bodies take on their specialised fates. The mechanisms which underlie the processes are described for the embryo and in the adult.