Cellular Adhesion

Brian W. Metcalf

ISBN 10: 0306446855 / ISBN 13: 9780306446856

Published by Springer US, Springer New York Jul 1994, 1994

About this Item

This item is printed on demand - Print on Demand Titel. Neuware -This volume focuses on recent developments in our understanding of selected adhesion processes that may offer new approaches to developing therapeutics for a variety ofdiseases. The volume first introduces the molecules involved in key adhesive processes, then describes the biological consequences of several adhe sive interactions, and closes with a description of the initial therapeutic ap proaches to antagonizing. adhesion. These papers were originally presented at the SmithKline Beecham Pharmaceuticals Seventh U. S. Research Symposium held in Philadelphia in October of 1992. ofacell to asurface. In its simplestsense, cellularadhesion is the adherence The cells of interest in the context of this volume are bacterial and mammalian, with an emphasis on leukocytes; surfaces can be other cells and tissues (such as bone), matrix proteins, or inanimate objects such as in-dwelling medical devices and catheters. Interaction between adhesion molecules usually results in a spe cific biological response. Adhesion is a form ofcellularcommunication, and represents the way a cell senses its environment through contact. Like hormones and cytokines, the sol uble mediators used by cells for communication, adhesion molecules are defined molecular entities that recognize specific receptor structures on the surface to which they adhere. Recent activity has focused on defining the structure of the individual molecules responsible for many types ofcellularadhesion. New adhe sion proteins are being cloned with the help of specific antibodies and precise functional assays.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 350 pp. Englisch.

Seller Inventory # 9780306446856

Bibliographic Details

• Title: Cellular Adhesion
• Publisher: Springer US, Springer New York Jul 1994
• Publication Date: 1994
• Language: English
• ISBN 10: 0306446855
• ISBN 13: 9780306446856
• Binding: Buch
• Condition: Neu
• Dimensions: 286W x 215H x 26D millimeters 286 millimeters width by 215 millimeters height by 26 millimeters depth
• Weight: 1215 grams

About this title

Synopsis

The books in this acclaimed series provide integrated, critical surveys of topics of current interest to the pharmaceutical industry. Cellular Adhesion: Molecular Definition to Therapeutic Potential covers the molecular definition of adhesion molecule structure and function, the biological consequences of cellular adhesion, and the therapeutic potential of targeting adhesion molecules.