Cellular Aging and Cell Death

Holbrook

ISBN 10: 0471121231 / ISBN 13: 9780471121237

Published by John Wiley and Sons Ltd, 1995

About this Item

Programmed cell death, or apoptosis, has become one of the hottest research areas in cell biology. its importance has been recognized in a variety of specialties. Basic gerontology research has seen strong growth spurred by the aging of the population. Editor(s): Holbrook, N. J.; Martin, G. R.; Lockshin, R. A. Series: Modern Cell Biology. Num Pages: 336 pages, Illustrations. BIC Classification: MJX; PSD; PSF. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 255 x 179 x 18. Weight in Grams: 604. . 1995. 1st Edition. Paperback. . . . . Books ship from the US and Ireland.

Seller Inventory # V9780471121237

Bibliographic Details

• Title: Cellular Aging and Cell Death
• Publisher: John Wiley and Sons Ltd
• Publication Date: 1995
• Language: English
• ISBN 10: 0471121231
• ISBN 13: 9780471121237
• Binding: Soft cover
• Condition: New

About this title

Synopsis

Cellular AGING AND CELL DEATH

Edited by Nikki J. Holbrook, George R. Martin, and Richard A.Lockshin

Cellular Aging and Cell Death provides a thorough understanding ofthe mechanisms responsible for cellular aging, covering the recentresearch on programmed cell death and senescence, and describingtheir role in the control of cell proliferation and the agingprocess. This one-of-a-kind book is the first to combine the twohottest research areas of cell biology into one comprehensivetext.

Leading experts contribute to give readers an authoritativeoverview of the distinct fields of cellular aging and programmedcell death, as well as to demonstrate how both fields are criticalto understanding the aging process. They address the large andgrowing interest in apoptosis, especially with regard to themolecular signals that induce and regulate programmed cell death,and the role of apoptosis in a variety of age-associated diseasesand disabilities. Throughout the book, a strong emphasis is placedon the interrelationship of the molecular, cellular, andphysiological aspects of senescence.

Individual chapters discuss such topics as the role and regulationof apoptosis in development, the potential impact of cell death onsuch postmitotic tissues as nerve and muscle, and suggest thatprogrammed cell death plays an important role in both pathologicaland nonpathological aspects of aging, including neurodegenerativediseases.

One important chapter focuses on the most recent research involvingthe study of telomeres, whose reduction in length with age and celldivision may underlie cellular senescence. The subject of neuronalcell death is also put into the perspective of aging.

Cellular Aging and Cell Death bridges the rapidly growing fields ofcellular aging and programmed cell death. This thorough, yetconcise book will be of particular interest to graduate studentsand researchers within the fields of cell and developmentalbiology, neurobiology, immunology, and physiology. Physicians andmedical students involved in the fields of gerontology andpathology will also find this an informative reference.

About the Author

Nikki J. Holbrook and George R. Martin are the authors of Cellular Aging and Cell Death, published by Wiley.