x, 408 p. 26 cm. Some b&w figures. White hardcover with black print. Spine ends softened. Corners bumped. Bookplate and former owner's signature on front free endpaper. An occasional ink mark and a thumb mark on title. Overall clean. Topics include: historical overview of research on cholinergic systems and behavior; cholinergic pathways in the brain; functions of central cholinergic systems in brain behavior; new aspects on the functional role of acetylcholine in the basal ganglia system; central cholinergic involvement in learning and memory; cholinergic mechanisms in aggressive behavior; cholinergic mechanisms, schizophrenia and neuropsychiatric adaptive dysfunctions; acetylcholine and attentional disorder; pharmacology of central cholinergic mechanisms and schizophrenic disorders; brain cholinergic systems and the pathogenesis of affective disorders; cholinergic neuropsychopharmacology and neuropathology of dementias; adaptive brain processes and psychopathology.

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Bibliographic Details

Title

Central Cholinergic Mechanisms and Adaptive Dysfunctions

Publisher

Plenum Press, New York

Publication Date

1985

ISBN 10

0306418355

ISBN 13

9780306418358

Binding

Hardcover

Condition

Very good

Seller catalogs

Medical

About this title

Synopsis

Although serious interest in studying the role of central cho linergic processes in psychopathology is just beginning to emerge, experimental literature on the part played by cholinergic mechanisms in brain behavior. reiations is quite extensive. During the past thirty years, cholinergic research has contributed significantly to the characterization and differentiation of adaptive mechanisms in volved in input selection, perception, cortical, autonomic and behav ioral activation, learning, memory, and inhibitory control of behav ioral outputs. To say that dysfunction of one or more of these mech anisms may be at the root of neuropsychiatric illnesses such as schiz ophrenia would be stating the obvious. This book examines the part cholinergic processes might play in dysfunctions of the adaptive processes involved in higher brain func tions and their significance for the pathogenesis, classification, etiology, and treatment of psychopathological conditions. In a series of wide ranging reviews of the available information, the subject is discussed from a variety of perspectives, using data derived from both experimental and clinical research. The purpose is not so much to determine whether cholinergic excess or deficiency is causal in this or that neuropsychiatric syndrome, but rather to try to understand the disease mechanisms in terms of adaptive processes in which cholinergic systems seem to play an important part."

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