Central Neural Control of the Kidney
Language: English
Published by VDM Verlag, 2008
- Softcover
- New

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Softcover
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- Title
- Central Neural Control of the Kidney
- Author
- Sly, David
- Publisher
- VDM Verlag
- Publication year
- 2008
- Condition
- New
- Binding
- Soft cover
- Language
- English
- ISBN 10
- 3639092082
- ISBN 13
- 9783639092080
This study was undertaken to locate and characterisethe neurons in the central nervous system that project to thekidney. A retrograde transsynaptic viral tracer was injected into thekidney of rats and traced through the neuraxis to locate these neurons. The results show that a polysynaptic neural pathway extends frommultiple forebrain sites including several novel autonomicsites, and projects successively through the brainstem, spinal cord andperipheral ganglia en route to the kidney. This pathway is activated inresponse to stimuli associated with the regulation of body fluidbalance. Both classical amino acid transmitters, and neuropeptideslikely mediate these effects. This work lays the foundation forpotential therapeutics in the treatment conditions of renal failure in whichthe central circuitry projecting to the renal nerves is compromised.
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About the Author
Dr David Sly is a neuroscientist with interests in centralneuroanatomy and neurochemistry, auditory physiology and neural prostheses. Hehas examined the central pathways controlling the kidney, neural arousal in Sudden Infant Death Syndrome and currently, biological strategiesaimed at improving cochlear implant function.
"About the title" may belong to another edition of this title.
Ria Christie Collections
Uxbridge, United Kingdom
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