Cerebral Venous System in Acute and Chronic Brain Injuries (Springer Series in Translational Stroke Research)

Provides important information from anatomy to pathophysiology and covers most neurological disorders that involve venous circulation. Venous circulation has not been extensively studied and we know relatively little about cerebral venous circulation. Venous circulation contributes to half of the brain circulation and about 70% of the blood in the brain is venous blood. Veins and venules play extremely important roles in brain circulation especially during pathologies such as brain edema, BBB disruption, elevation of intracranial pressure during and after ischemic and hemorrhagic stroke events, traumatic brain injury, neurodegerative disorders, in adults and newborns. Occlusion of veins or sinuses by thrombus, compression of veins and venules by tumor and edematous tissues, elevation of venous pressure during cranial hypertension, all lead to fatal insults such as venous infarction and hemorrhage.

This volume is focused on subjects related to cerebral veins under normal conditions and after brain injuries especially acute stroke. Some chapters are selected from the Sixth Elite Stroke meeting named Pangu Stroke Conference and some chapters are invited, but all written by members of world leading laboratories of stroke and central nervous system studies. The contents cover both clinical and bench studies, from basic components of cerebral neurovascular network and venous stroke animal models to clinical venous disorders, from venous imaging, venous regulation, and venous collateral circulation to acute and chronic brain injuries including pediatric and neurosurgical disorders to hemorrhagic stroke.