Characterization of Chemical Purity: Organic Compounds (IUPAC Publications)

The Characterization of Chemical Organic Compounds focuses on the processes, methodologies, and reactions involved in chemical purity. The selection first offers information on the concept of purity and its bearing on methods used to characterize purity and thermal methods, including general observations on impurity determination, freezing and melting phenomena, and classification of thermal methods of purity control. The manuscript also takes a look at density measurements, refractive index, and vapor pressure and boiling temperature measurements. The book ponders on chromatography and mass spectrometry. Discussions focus on chromatograms, testing of purity, quantitative and qualitative analysis, and liquid chromatography. The text also reviews optical, Raman, and nuclear magnetic resonance spectroscopy. Topics include infra-red (vibrational) spectra, experimental techniques, and nature of the Raman effect. Chemical and physical measurements, calibration of instruments, availability of standard reference materials, and value of human effort are discussed. The manuscript is a dependable reference for readers interested in chemical purity.